Our Experience and the Use of Technology are Unmatched
We profile compounds for emetic liability and anti-emetic potential and can perform very basic-to-complex experiments, depending on individual clients' needs.
We are experts in the use of radiotelemetry to simultaneously measure behavior and the effect of drug treatment on cardiovascular parameters (blood pressure, heart rate, etc.) and gastric myoelectric activity during behavior, to identify and dissociate side effect profiles.
We use c-fos immunohistochemistry to study brainstem areas involved in emesis control, and a combination of forebrain areas, that may be involved in the control of nausea.
We routinely administer drugs via peripheral (oral, intravenous, subcutaneous, intraperitonal, intramuscular, and instra-tracheal) and central (intraventricular and intracerebral) routes to provide detailed dose-response information.
We lead the world in experimentation of gastric dysthryhmia using advanced radiotelemetric recording techniques in ferret, Suncus murinus, and mouse models.
We profile compounds for emetic liability and anti-emetic potential and can perform very basic-to-complex experiments, depending on individual clients' needs.
We are experts in the use of radiotelemetry to simultaneously measure behavior and the effect of drug treatment on cardiovascular parameters (blood pressure, heart rate, etc.) and gastric myoelectric activity during behavior, to identify and dissociate side effect profiles.
We use c-fos immunohistochemistry to study brainstem areas involved in emesis control, and a combination of forebrain areas, that may be involved in the control of nausea.
We routinely administer drugs via peripheral (oral, intravenous, subcutaneous, intraperitonal, intramuscular, and instra-tracheal) and central (intraventricular and intracerebral) routes to provide detailed dose-response information.
We lead the world in experimentation of gastric dysthryhmia using advanced radiotelemetric recording techniques in ferret, Suncus murinus, and mouse models.